Wang Kaijun   M.D., Ph.D.

Academic Rank:Chief Physician
Position:Vice Chair of Ophthalmology
Clinical / Research Interests
Diagnosis and treatment of primary and secondary glaucoma, especially glaucoma and cataract surgery, drainage valve implantation, CLASS surgery, and galucoma laser treatment.
Professional Appointments

Young Member, Chinese Society of Ophthalmology, Chinese Medical Association            

Member, Glaucoma Group, Chinese Society of Ophthalmology, Chinese Medical Association                   

Vice Chair, Ophthalmology Youth Committee, Zhejiang Medical Doctor Association

Research Summary

Role and mechanism of HCMV gB genotype mediated cell infection tropism in the pathogenesis of glaucoma associated with inflammation 

Study of silicon sponge implantation in the scleral reservoir and its application in CO2 laser-assisted(CLASS)deep sclerectomy

Publications

Chen M,Wu A, Zhang L, Wang W, Chen X, Yu X,Wang K* .The increasing prevalence of myopia and high myopia among high school students in Fenghua city, eastern China: a 15-year population-based survey. BMC Ophthalmology. 2018; 18:159-169.

Zhang L, Hu Y, Huang W, Ni L, Wu B, Gao H, Ye X, Liu L, Chen M, Wang K*. Different energy densities of Nd:YAG laser iridotomy in treatment of angle-closure glaucoma. Int J Clin Exp Med. 2017; 10(9): 13452-13457.

Chen M, Liu B, Ma J, Ge J, Wang K*. Protective effect of mitochondria targeted peptide MTP131 against oxidative stress induced apoptosis in RGC5 cells. Mol Med Rep. 2017, 15: 2179-2185. 

Chen M, Wang Wei, Ma Jian, Ye Panpan, Wang K*. High glucose induces mitochondrial dysfunction and apoptosis in human retinal pigment epithelium cells via promoting SOCS1 and Fas/FasL signaling. Cytokine, 2016; 78: 94-102. 

Wang K, Zhu M, Ye P, Chen G, Wang W, Chen M. Ionizing radiation-induced microRNA expression changes in cultured RGC-5 cells. Mol Med Rep. 2015 Sep; 12 (3): 4173-8. 

Wang K, Jiang Y, Wang W, Ma J, Chen M. Escin activates AKT-Nrf2 signaling to protect retinal pigment epithelium cells from oxidative stress. Biochem Biophys Res Commun. 2015 Dec 25; 468 (4): 541-7.

Wang K, Liu J, Chen M. Role of B-scan ultrasonography in the localization of intraocular foreign bodies in the anterior segment: a report of three cases. BMC Ophthalmology. 2015; 15:102-107.

Wang K, Li Xia, Lou HY, Luo BY. Recurrent attacks of headache and neck pain caused by congenital aplasia of the posterior arch of atlas in an adult. BMJ Case Reports, Published 2 November 2010; doi: 10.1136/bcr.05.2010.3053.

Yu Y, Yao K, Wu W, Wang K, Chen G, Lu D. Effects of exposure to 1.8 GHz radiofrequency field on the expression of Hsps and phosphorylation of MAPKs in human lens epithelial cells. Cell Res. 2008; 18(12): 1233-1235.

1Yao K, Wu W, Wang K, Ni S, Ye P, Yu Y, Ye J, Sun L. Electromagnetic noise inhibits radiofrequency radiation-induced DNA damage and reactive oxygen species increase in human lens epithelial cells. Molecular Vision, 2008; (14): 964-969.

Wang K, Cheng C, Li L, Liu H, Huang Q, Xia CH, Yao K, Sun P, Horwitz J, Gong X. GammaD-crystallin associated protein aggregation and lens fiber cell denucleation. Invest Ophthalmol Vis Sci. 2007; 48 (8): 3719-3728.

Yao K, Tan J, Ye P, Wang K, Xu W, ShenTu X, Tang X. Integrin beta1-mediated signaling is involved in transforming growth factor-beta2-promoted migration in human lens epithelial cells. Molecular Vision 2007, 20;13: 1769-1776.

Yao K, Yu Y, Wang K, Ye J, Lu D, Jiang H. Absence of effect of power-frequency magnetic fields exposure on mouse embryonic lens development. Bioelectromagnetics. 2007; 28(8): 628-635.

Yao K, Tan J, Gu WZ, Ye PP, Wang K. Reactive oxygen species mediates the apoptosis induced by transforming growth factor beta(2) in human lens epithelial cells. Biochem Biophys Res Commun. 2007; 354(1):278-283.

Sun LX, Yao K, Wang K, Lu DQ, Hu HJ, Gao XW, Wang BH, Zheng W, Lou JL, Wu W. Effects of 1.8GHz radiofrequency field on DNA damage and expression of heat shock protein 70 in human lens epithelial cells.  Mutat Res 2006 Sep 29: 135-142.

Yao K, Sun ZH, Shentu XC, Wang K, Tan J. Computer construction and analysis of protein models of the mutant gammaD-crystallin gene. Chinese Medical Journal 2005;118(9):738-741.

Yao K, Tang X, Shentu XC, Wang K, Rao H, Xia K. Progressive polymorphic congenital cataract caused by a CRYBB2 mutation in a Chinese family.  Molecular Vision 2005;11:758-763.

Wang K, Liu H, Xia C. A new mouse mutation develops nuclear cataract in heterozygote while posteriorly ruptured lens in homozygote. Invest Ophthalmol Vis Sci, 2005, 46: E822 (Abstract)

Yao K, Wang K, Sun ZH, Tan J, Xu W, Zhu LJ, Lu DQ. Low power microwave radiation inhibits the proliferation of rabbit lens epithelial cells by upregulating P27Kip1 expression. Molecular Vision 2004; 10(2): 138-143.  

Xu W, Yao K, Sun ZH, Wang K, Shentu XC. Expression and proteolytic activity of calpain in lens epithelial cells of oxidative cataract.  Journal of Zhejiang University SCIENCE 2004;5(6): 743-748.

Yao K, Wang K, Xu W, Sun Z, Shentu X, Qiu P. Caspase-3 and its inhibitor Ac-DEVD-CHO in rat lens epithelial cell apoptosis induced by hydrogen in vitro. Chin Med J 2003; 116(7): 1034-1038.

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