Screening and function investigation of congenital cataract linked mutation from cataract patients; Molecular mechanism investigation of human lens development and congenital cataract progress using iPSCs derived regenerative lens through our newly developed 'fried egg' lentoid body differentiation method; Investigation of the pathogenic mechanisms of age-related cataract; Invention of IOLs loaded with sustained-release drugs using 3D printing, layer-by-layer method, etc.
Danni Lyu, Siham Almansoob, Hui Chen, Yang Ye, Fan Song, Lifang Zhang, Zhenwei Qin, Qiaomei Tang, Houfa Yin, Wen Xu, Zhijian Chen, Ke Yao 3*, Qiuli Fu 4*. Transcriptomic Profiling of Human Corneal Epithelial Cells Exposed to Airborne Fine Particulate Matter (PM 2.5). Ocul Surf. 2020 Jun 18;S1542-0124(20)30100-2.
Siyu Liu, Chenyang Hu, Yueqiu Luo, Ke Yao*. Genome-wide DNA Methylation Profiles May Reveal New Possible Epigenetic Pathogenesis of Sporadic Congenital Cataract. Epigenomics. 2020 Jun 9.
Yueyang Zhong, Kai Wang, Yanan Zhu, Danni Lyu, Ke Yao*. COVID-19 and the Eye. J Infect. 2020 May 28;S0163-4453(20)30331-5.
Yue-Ye Wang, Ke-Yao Zhou, Yang Ye, Fan Song, Jin Yu, Jin-Cao Chen, Ke Yao*. Moyamoya Disease Associated With Morning Glory Disc Anomaly and Other Ophthalmic Findings: A Mini-Review. Front Neurol. 2020 May 15;11:338.
Yue Huang, Qiang Gao, Xu Li1, Yifan Gao, Haijie Han, Qiao Jin*, Ke Yao, and Jian Ji. Ofloxacin loaded MoS2 nanoflakes for synergistic mild-temperature photothermal/antibiotic therapy with reduced drug resistance of bacteria. Nano Res. (2020).
Haijie Han, Qichuan Yin, Xiajing Tang, Xiaoning Yu, Qiang Gao, Yelei Tang, Andrzej Grzybowski, Ke Yao, Jian Ji, Xingchao Shentu*. Development of Mucoadhesive Cationic Polypeptide Micelles for Sustained Cabozantinib Release and Inhibition of Corneal Neovascularization. J. Mater. Chem. B, 2020,8, 5143-5154.
Dengfeng Hu, Lingyun Zou, Weijiang Yu, Fan Jia, Haijie Han, Ke Yao, Qiao Jin, Jian Ji*. Relief of Biofilm Hypoxia Using an Oxygen Nanocarrier: A New Paradigm for Enhanced Antibiotic Therapy. Adv. Sci. 2020.
Yang X, Xu J, Fu C, Jia Z, Yao K*, Chen X*. The cataract-related S39C variant increases γS-crystallin sensitivity to environmental stress by destroying the intermolecular disulfide cross-links. Biochem Biophys Res Commun. 2020 Mar 28. 526 (2020) 459-465.
Song X, Liu X, Wang W, Zhu Y, Qin Z, Lyu D, Shentu X, Xv W, Chen P, Yao KE*. Visual Outcome and Optical Quality after Implantation of Zonal Refractive Multifocal and Extended Range of Vision Intraocular Lenses: A Prospective Comparison. J Cataract Refract Surg. 2020 Jan 30.
Qiao Y, He J, Chen W, Yu Y, Li W, Du Z1, Xie T, Ye Y, Hua SY, Zhong D, Yao K, Zhou M*. Light-Activatable Synergistic Therapy of Drug-Resistant Bacteria-Infected Cutaneous Chronic Wounds and Nonhealing Keratitis by Cupriferous Hollow Nanoshells. ACS Nano. 2020 Mar 24;14(3):3299-3315.
Tang X#, Lou L#, Xu Y, Jin K, Cao J, Shao J, Gao Z, Yao K*. Socioeconomic inequality in the global burden of refraction disorders: results from the Global Burden of Diseases Study 2017. Acta Ophthalmol. 2020 Mar 1.
Li J, Chen X, Yan Y, Yao K*. Molecular genetics of congenital cataracts. Exp Eye Res. 2020 Feb;191:107
Professional Highlights
State Scientific and Technological Progress Award, Second Prize
Zhejiang Scientific and Technological Progress Award, First Prize
Zhejiang Province Extraordinary Contributor for Science and Technology
Alfred Vogt-Prize, Switzerland
ICO Mark Tso Golden Apple Award
APACRS Golden Award
APACRS A.C.E Award
Italian Ophthalmic Society Antonio SCARPA Medal
International Lecture Medal
US-Sino Ophthalmology Golden Key Award
US-Sino Ophthalmology Golden Apple Award
Outstanding Achievement Award of COS
Chinese Physician Award
Professional Appointments
Chair, Chinese Ophthalmological Society
Chair, Chinese Cataract Society, 2007-present
Committee Member, International Council of Ophthalmology
Member, Academia Ophthalmologica Internationalis
Regional Secretary, Asia-Pacific Academy of Ophthalmology
President, Asia-Pacific Association of Cataract & Refractive Surgeons
Council Member, Academy of Asia-Pacific Professors of Ophthalmology
Member, International Intra-Ocular Implant Club
Chair, Zhejiang Association for Science and Technology
Chair, Zhejiang Medical Association
Editor-in-Chief, Ophthalmology (Chi)
Editor-in-Chief, EyeWorld in Asia-Pacific Version (Chi)
Editor-in-Chief, Chinese Journal of Ophthalmology (Chi)
Deputy Editor-in-Chief, International Journal of Ophthalmology
Deputy Editor-in-Chief, Chinese Journal of Experimental Ophthalmology (Chi)
Editor, Graefe's Archive for Clinical and Experimental Ophthalmology
Editor, Asia-Pacific Journal of Ophthalmology
Editor, Translational Vision Science & Technology
Editor, Ophthalmic Research
